Wednesday, December 31, 2003

BBC NEWS | Health | Garlic could provide cancer drug: "The chemical which gives garlic its flavour could be used in a 'smart bomb' to fight cancer, scientists say. " IMPORTANT

Wednesday, December 17, 2003

Triple Therapy Better Than Mixed Insulin for Obese Type 2 DM: "Dec. 5, 2003 � Combining rosiglitazone, metformin, and insulin aspart improved glucose metabolism in obese type 2 diabetic patients compared with mixed insulin alone, according to the results of a open-label, randomized trial published in the December issue of Diabetes Care"

READ

Monday, December 15, 2003

MSN Hotmail - More Useful Everyday: "Accommodating Intraocular Lenses Allow Near and Far Vision: A Newsmaker Interview With J. Stuart Cumming, MD, FACS, FRCOphth"

Thursday, December 11, 2003

The Channel Issue 3: "



People with Diabetes Can Enjoy Their Favorite Foods

Many people think that having diabetes means you can't eat your favorite foods. Well, it's not true. You can still eat the foods you love. Food means family, friends, comfort, and pleasure, not just vitamins and minerals. That's why, for most people, food is the hardest part of caring for diabetes. Your dietitian will show you how to include your favorites and still keep your blood sugar on track.



Making changes in the way you eat or the times you eat can be tough. Remember that it's up to you to work with your health care team and tell them what will work for you. Decide what changes you'd like to try and work on one at a time. Whether you'd rather eat noodles or tacos, using a meal plan is a great way to keep blood sugar on target.

Talk to your dietitian about your schedule, how active you are, and where you go when you eat out. The two of you will design a plan that will fit the way you live and the foods you and your family like, and help you feel good and stay healthy.





NEXT FEATURE"

Wednesday, December 10, 2003

Diabetes: Information from WebMD: "Diabetes Health Center

Diabetes affects an estimated 17 million Americans, and the number rises each year. Find in-depth information here about diabetes prevention, diet, treatments, and research. Plus, find daily support and nutritional tips in our online message boards. "

Tuesday, December 09, 2003

Autism Society of America: Aspergers: "Asperger's Disorder is one of five Pervasive Development Disorders (PDDs), which also includes Autism, Rett's Syndrome, Childhood Disintegrative Disorder, and PDD-Not Otherwise Specified (PDD-NOS). PDDs are a category of neurologically-based disorders that have a range of delays in different developmental stages. "

Monday, December 08, 2003

Arthritis, Joint inflammation - Causes, Treatment and Prevention

Definition
Arthritis is a disease that involves inflammation of one or more joints.
("Arthr" refers to joints, and "itis" to inflammation).

Cause
Joint inflammation is the body's reaction to various disease processes. These include mechanical injury to a joint (including fracture), the presence of an infection (usually caused by bacteria or viruses), an attack on the joints by the body itself (an autoimmune disease), or accumulated "wear and tear" on joints.

Monday, December 01, 2003

Future Heart Attacks - BP & CRP - Heart: health and medical information about heart disease and other cardiovascular conditions

Background: It is well known that having high blood pressure increases the risk of having a heart attack. Accumulating data also suggest a link between blood pressure and vascular inflammation. CRP (C-reactive protein) is linked to low-level ongoing inflammation. But is there a relationship between having high blood pressure and elevated CRP levels?

Thursday, November 20, 2003

MSN Hotmail - More Useful Everyday: "One Third of Sleep Apnea Patients in Study Diagnosed With Glaucoma


Medscape Medical News 2003. � 2003 Medscape

Karla Harby
Nov. 18, 2003 (Anaheim) � In an ongoing, prospective study of 83 patients with obstructive sleep apnea (OSA), glaucoma was diagnosed in 27 (33%) of the study subjects. Only four had been previously diagnosed and treated, according to Rick E. Bendel, MD, from the Mayo Clinic in Jacksonville, Florida.
Based on this and earlier observations suggesting an association between the two conditions, Dr. Bendel recommends that all sleep apnea patients be screened for glaucoma. 'OSA may be a modifiable risk factor that is easily treatable,' he told an audience at the annual meeting of the American Academy of Ophthalmology.
The moderator of the session, James C. Tsai, MD, from Columbia University in New York City, spoke with Medscape afterward and said that the 33% prevalence of glaucoma found in this population '...is a big deal...' compared with the 1.5% to 2.5% prevalence of this disease in the general population. 'This is underappreciated,' he added. 'As more prospective series are done, we're going to have to address this with our patients.'
Karanjit S. Kooner, MD, from the University of Texas at Dallas, agreed that patients with sleep apnea are prime candidates for thorough ophthalmologic examinations. 'This study shows, in a very well designed fashion, that there is another risk factor for glaucoma for us to consider,' he told attendees during his discussion. 'These patients need to be sent to sleep disorder centers. There is a lot of good treatment "


Medscape Medical News 2003. © 2003 Medscape




Karla Harby

Nov. 18, 2003 (Anaheim) — In an ongoing, prospective study of 83 patients with obstructive sleep apnea (OSA), glaucoma was diagnosed in 27 (33%) of the study subjects. Only four had been previously diagnosed and treated, according to Rick E. Bendel, MD, from the Mayo Clinic in Jacksonville, Florida.

Based on this and earlier observations suggesting an association between the two conditions, Dr. Bendel recommends that all sleep apnea patients be screened for glaucoma. "OSA may be a modifiable risk factor that is easily treatable," he told an audience at the annual meeting of the American Academy of Ophthalmology.

The moderator of the session, James C. Tsai, MD, from Columbia University in New York City, spoke with Medscape afterward and said that the 33% prevalence of glaucoma found in this population "...is a big deal..." compared with the 1.5% to 2.5% prevalence of this disease in the general population. "This is underappreciated," he added. "As more prospective series are done, we're going to have to address this with our patients."

Karanjit S. Kooner, MD, from the University of Texas at Dallas, agreed that patients with sleep apnea are prime candidates for thorough ophthalmologic examinations. "This study shows, in a very well designed fashion, that there is another risk factor for glaucoma for us to consider," he told attendees during his discussion. "These patients need to be sent to sleep disorder centers. There is a lot of good treatment available."

Dr. Bendel's team used the strictest criteria in this study for diagnosis of sleep apnea, an apnea-hypopnea index (AHI) of at least 15. According to Dr. Bendel, this meant that apnea, hypopnea or both occurred 15 or more times per hour in these subjects. Glaucoma was defined as multifactor optic neuropathy diagnosed by changes in the optic nerve, or abnormalities of the visual field, or both.

"Our study rationale looked at OSA because it causes profound changes in oxygenation, circulatory hemodynamics, and inflammatory factors," Dr. Bendel said. "All of these may influence optic nerve integrity and possibly intraocular pressure, as well."

This interim analysis was based on 83 of 100 patients expected to participate. Among the study subjects, six were nonwhite and 51 (61%) were men. The median age was 62 years; the median body mass index (BMI) was 35 (with a BMI of 30 or greater defining obese); and the median AHI was 37 — "meaning a lot of our patients stopped breathing about 40 or more times per hour," Dr. Bendel explained. Median intraocular pressure (IOP) was 16 mm Hg.

Two of the patients under study (2.4%) had ocular hypertension. "This is something I would expect in the population at large," Dr. Bendel said. "However, I wasn't expecting to find 33% of the patients with a diagnosis of glaucoma." Of these, 17 patients (63%) had glaucoma using the more strict definition of visual field plus optic nerve abnormalities; six patients (22%) were diagnosed by optic nerve changes alone; and four patients (15%) had a previous diagnosis and treatment by an outside ophthalmologist.

None of the variables examined, including age, sex, BMI, AHI, and IOP, were statistically significant predictors of which patients would be diagnosed with glaucoma, Dr. Bendel reported. Associating these same variables with IOP, only two showed statistical significance: the IOP tended to be lower in men (P = .04), and as the BMI increased, the IOP increased (P = .04). Specifically, the IOP increased about 0.5 mm Hg per an increase of five units of BMI, he said.

Patients with OSA are already known to be at higher risk for motor vehicle collisions, myocardial infarctions, strokes, and premature death. "Perhaps glaucoma will one day be added to this list," Dr. Bendel said.

This study was independently funded. The authors reported no pertinent financial disclosures.

AAO 2003 Annual Meeting: Free Papers. Presented Nov. 17, 2003.

Reviewed by Gary D. Vogin, MD

Karla Harby is a freelance writer for Medscape

Saturday, November 15, 2003